Product Info.
 
Gonadorelin Acetate
CAS No. 34973-08-5
Molecular Formula C55H75N17O13
Molecular Weight 1182.3
Storage 2~8℃
Batch No. 20070523
Manufacturing Date 2007-05-24
Retest Date 2009-05-23
Sequence pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
TEST ITEMS SPECIFICATION RESULT
1 Assay(ByAnhydrous,AceticAcid-free) 95.0~102.0% 98.5%
2 Appearance White to Off-white powder Complies
3 Solubility Soluble in water and in a 1% glacial acetic acid Complies
4 Identity (by HPLC) The retention is same with the reference substance Complies
5 Identity (by TLC) The principal spot corresponds in position and size to the reference substance Complies
6 Appearance of Solution 10mg/ml solution is clear and not more intensely colored than reference solution Complies
7 Specific Optical Rotation -54.0~-66.0°(c=1,1%HAc) -62.8°
8 Absorbance (by UV) 0.55~0.61 (c=0.1mg/ml H2O, λmax=278nm 0.57
9 Amino Acid Composition Ser:0.7~1.05 Glu:0.95~1.05 Pro:0.95~1.05 Gly:1.90~2.10 Leu:0.90~1.10 Tyr:0.7~1.05 His:0.95~1.05 Arg:0.95~1.05 Trp: Presnt 0.93 0.98 1.02 2.01 0.95 1.01 0.99 1.00 Present
10 Related Substance (By HPLC) Total Impurities (%)≤5.0% Largest Single Impurity (%)≤ 2.0% 1.5% 0.6%
11 Acetate Content (By HPLC) 4.0~7.5% 4.7%
12 Water Content (Karl Fischer) ≤7.0% 2.7%
13 Bacterial Endotoxins ≤70IU/mg Complies